Global FIA has just been awarded a patent (USP 8,365,616) for its versatile Sampling Probe developed by Woody Wolcott and Graham Marshall. This probe includes a small 3-way valve developed by Wolcott that enables the user to carry out a range fo fluid manipulation steps right at the sample probe in close-proximity to the sampling point.
The probe was initially developed to allow for sampling of super-saturated samples which are prone to come out of solution with cooling. By carrying out a dilution step right at the sampling point the compound is diluted before it can clog up narrow transfer lines.
Various accessories and attachments allow sampling from:
- Batch reactors
- Homogenous room temperature reactors
- Heterogeneous room temperature reactors where the liquid phase or sample containing solids is required
- Reactors at elevated temperatures containing supersaturated solutions
- Miniature reactors where probe size is a constraint
- Flow through reactors
- The headspace of reactors
The probe can be equipped with a range of tips including various filters as depicted in the following picture.
The simplest probe tip provides no sample conditioning and is a straightforward 0.03” ID inlet (A). This tip can be equipped with a stainless steel 75 µm screen (B). Several filter elements have been developed. Each filter element is replaceable. The large volume filter element is equipped with a 2cm long 25µm porous Teflon filter (C). The small volume filter is equipped with a 7mm 2µm filter (D). The flat bottom filter tip allows sampling from shallow reactors (E) and has a filter surface area of 30 mm2 and can be equipped with any filter disk. The sterile barrier filter is equipped with a 7mm 0.2µm filter (F). Syringe filters can be attached to the luer fitting tip (G).